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Pantothenic Acid

Recommended Daily Allowance

America Australia UK
4-7 mg n/a n/a

Uses and Facts

Pantothenic acid, which is also known as vitamin B5, takes its name from the Greek word 'panto' meaning 'everywhere' as it is found in a wide range of foods. It can also be made by intestinal bacteria. 

METABOLISM

Pantothenic acid is essential for the release of energy from food. It is used in the manufacture of a compound called coenzyme A which plays a vital role in the breakdown of fats and carbohydrates. 

BRAIN AND NERVOUS SYSTEM

Pantothenic acid is necessary for the production of some neuro- 

transmitters such as acetylcholine and is essential for normal nervous system function. 

IMMUNE SYSTEM

Antibody synthesis requires pantothenic acid and it is also involved in wound healing. 

ADRENAL GLANDS

Normal adrenal gland function requires pantothenic acid as it is essential for production of adrenal hormones such as cortisone. These hormones play an essential part in the body’s reaction to stress. 

RED BLOOD CELLS

The formation of healthy red blood cells requires pantothenic acid as it is involved in the production of compounds needed to make hemoglobin. 

Absorption

Pantothenic acid is absorbed from the intestine and excesses are excreted in the urine. The body has a limited ability to store pantothenic acid. 

Deficiency

A deficiency of pantothenic acid has not been found in human beings but has been induced under experimental conditions. It causes the adrenal glands to shrink with symptoms of fatigue, headache, sleep disturbances, personality changes, nausea and abdominal distress. Other symptoms of deficiency include numbness and tingling of the hands and feet, muscle cramps, impaired coordination, immune problems, dermatitis and itching. 

Sources

Good natural sources of pantothenic acid include yeast, liver, eggs, wheatgerm, bran, peanuts, peas, meat, milk, poultry, whole grains, broccoli, mushrooms and sweet potatoes. Most vegetables and fruits contain small amounts. Heat, food processing techniques and canning destroy pantothenic acid. 

Supplements

Pantothenic acid is usually present in oral supplements as calcium pantothenate. Pantethine is the most stable active form of pantothenic acid. 

Interactions

Pantothenic acid works with carnitine and coenzyme Q10. Sulfa drugs, sleeping pills, estrogen and alcohol may raise pantothenic acid requirements.

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